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The DNA intercalators ethidium bromide and propidium iodide also bind to core histones
Eukaryotic DNA is compacted in the form of chromatin, in a complex with histones and other non-histone proteins. The intimate association of DNA and histones in chromatin raises the possibility that DNA-interactive small molecules may bind to chromatin-associated proteins such as histones. Employing...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958746/ https://www.ncbi.nlm.nih.gov/pubmed/24649406 http://dx.doi.org/10.1016/j.fob.2014.02.006 |