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Effects of antidromic and orthodromic activation of STN afferent axons during DBS in Parkinson's disease: a simulation study

Recent studies suggest that subthalamic nucleus (STN)-Deep Brain Stimulation (DBS) may exert at least part of its therapeutic effect through the antidromic suppression of pathological oscillations in the cortex in 6-OHDA treated rats and in parkinsonian patients. STN-DBS may also activate STN neuron...

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Detalles Bibliográficos
Autores principales: Kang, Guiyeom, Lowery, Madeleine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958751/
https://www.ncbi.nlm.nih.gov/pubmed/24678296
http://dx.doi.org/10.3389/fncom.2014.00032