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Hypoxia Enhances Protective Effect of Placental-Derived Mesenchymal Stem Cells on Damaged Intestinal Epithelial Cells by Promoting Secretion of Insulin-Like Growth Factor-1

Apoptosis and necrosis of intestinal epithelial cells (IECs), induced by ischemia-reperfusion (I/R) injury, can lead to dysfunction of the intestinal barrier, which could cause multiple organ dysfunction syndromes. Mesenchymal stem cells (MSCs) have the potential of providing protective effects on d...

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Detalles Bibliográficos
Autores principales: Du, Lili, Yu, Yanqiu, Ma, Haiying, Lu, Xiaomei, Ma, Ling, Jin, Yunan, Zhang, Haipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958833/
https://www.ncbi.nlm.nih.gov/pubmed/24473145
http://dx.doi.org/10.3390/ijms15021983