shRNA-Mediated XRCC2 Gene Knockdown Efficiently Sensitizes Colon Tumor Cells to X-ray Irradiation in Vitro and in Vivo

Colon cancer is one of the most common tumors of the digestive tract. Resistance to ionizing radiation (IR) decreased therapeutic efficiency in these patients’ radiotherapy. XRCC2 is the key protein of DNA homologous recombination repair, and its high expression is associated with enhanced resistanc...

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Detalles Bibliográficos
Autores principales: Wang, Qin, Wang, Yan, Du, Liqing, Xu, Chang, Sun, Yuanming, Yang, Bing, Sun, Zhijuan, Fu, Yue, Cai, Lu, Fan, Saijun, Fan, Feiyue, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958843/
https://www.ncbi.nlm.nih.gov/pubmed/24481064
http://dx.doi.org/10.3390/ijms15022157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958843/
https://www.ncbi.nlm.nih.gov/pubmed/24481064
http://dx.doi.org/10.3390/ijms15022157

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