Xenobiotic Metabolism: The Effect of Acute Kidney Injury on Non-Renal Drug Clearance and Hepatic Drug Metabolism

Acute kidney injury (AKI) is a common complication of critical illness, and evidence is emerging that suggests AKI disrupts the function of other organs. It is a recognized phenomenon that patients with chronic kidney disease (CKD) have reduced hepatic metabolism of drugs, via the cytochrome P450 (C...

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Detalles Bibliográficos
Autores principales: Dixon, John, Lane, Katie, MacPhee, Iain, Philips, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958866/
https://www.ncbi.nlm.nih.gov/pubmed/24531139
http://dx.doi.org/10.3390/ijms15022538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958866/
https://www.ncbi.nlm.nih.gov/pubmed/24531139
http://dx.doi.org/10.3390/ijms15022538

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