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The Proteasome Activator PA28γ, a Negative Regulator of p53, Is Transcriptionally Up-Regulated by p53

PA28γ (also called REGγ, 11Sγ or PSME3) negatively regulates p53 activity by promoting its nuclear export and/or degradation. Here, using the RNA ligase-mediated rapid amplification of cDNA ends (RLM-RACE) method, we identified the transcription start site of the PA28γ gene. Assessment with the luci...

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Detalles Bibliográficos
Autores principales: Wan, Zhen-Xing, Yuan, Dong-Mei, Zhuo, Yi-Ming, Yi, Xin, Zhou, Ji, Xu, Zao-Xu, Zhou, Jian-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958868/
https://www.ncbi.nlm.nih.gov/pubmed/24531141
http://dx.doi.org/10.3390/ijms15022573