Pattern Recognition Techniques Applied to the Study of Leishmanial Glyceraldehyde-3-Phosphate Dehydrogenase Inhibition

Chemometric pattern recognition techniques were employed in order to obtain Structure-Activity Relationship (SAR) models relating the structures of a series of adenosine compounds to the affinity for glyceraldehyde 3-phosphate dehydrogenase of Leishmania mexicana (LmGAPDH). A training set of 49 comp...

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Detalles Bibliográficos
Autores principales: Lozano, Norka B. H., Oliveira, Rafael F., Weber, Karen C., Honorio, Kathia M., Guido, Rafael V. C., Andricopulo, Adriano D., de Sousa, Alexsandro G., da Silva, Albérico B. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958905/
https://www.ncbi.nlm.nih.gov/pubmed/24566143
http://dx.doi.org/10.3390/ijms15023186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958905/
https://www.ncbi.nlm.nih.gov/pubmed/24566143
http://dx.doi.org/10.3390/ijms15023186

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