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C2-Ceramide Induces Cell Death and Protective Autophagy in Head and Neck Squamous Cell Carcinoma Cells

Ceramides are second messengers involved in several intracellular processes in cancer cells, amongst others. The aim of this study was to evaluate the anti-tumor efficacy of C2-ceramide (C2-Cer; N-acetyl-d-sphingosine) by investigating cell death and autophagy in head and neck squamous cell carcinom...

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Detalles Bibliográficos
Autores principales: Zhu, Wenyuan, Wang, Xinhua, Zhou, Yi, Wang, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958915/
https://www.ncbi.nlm.nih.gov/pubmed/24566153
http://dx.doi.org/10.3390/ijms15023336