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The Mechanistic Links Between Proteasome Activity, Aging and Age-related Diseases

Damaged and misfolded proteins accumulate during the aging process, impairing cell function and tissue homeostasis. These perturbations to protein homeostasis (proteostasis) are hallmarks of age-related neurodegenerative disorders such as Alzheimer’s, Parkinson’s or Huntington’s disease. Damaged pro...

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Detalles Bibliográficos
Autores principales:	Saez, Isabel, Vilchez, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958958/ https://www.ncbi.nlm.nih.gov/pubmed/24653662 http://dx.doi.org/10.2174/138920291501140306113344

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