HIV-1 persistence in CD4(+) T cells with stem cell-like properties

Cellular HIV-1 reservoirs that persist despite antiretroviral treatment are incompletely defined. We show that during suppressive antiretroviral therapy, CD4(+) T memory stem cells (T(SCM)) harbor high per-cell levels of HIV-1 DNA, and make increasing contributions to the total viral CD4(+) T cell r...

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Detalles Bibliográficos
Autores principales: Buzon, Maria J., Sun, Hong, Li, Chun, Shaw, Amy, Seiss, Katherine, Ouyang, Zhengyu, Martin-Gayo, Enrique, Leng, Jin, Henrich, Timothy J., Li, Jonathan Z., Pereyra, Florencia, Zurakowski, Ryan, Walker, Bruce D., Rosenberg, Eric S., Yu, Xu G., Lichterfeld, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959167/
https://www.ncbi.nlm.nih.gov/pubmed/24412925
http://dx.doi.org/10.1038/nm.3445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959167/
https://www.ncbi.nlm.nih.gov/pubmed/24412925
http://dx.doi.org/10.1038/nm.3445

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