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Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signalling by controlling MyD88 turnover in Drosophila

Innate immunity mediated by Toll signalling has been extensively studied, but how Toll signalling is precisely controlled in balancing innate immune responses remains poorly understood. It was reported that the plasma membrane localization of Drosophila MyD88 is necessary for the recruitment of cyto...

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Detalles Bibliográficos
Autores principales: Ji, Shanming, Sun, Ming, Zheng, Xiudeng, Li, Lin, Sun, Liwei, Chen, Dahua, Sun, Qinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959197/
https://www.ncbi.nlm.nih.gov/pubmed/24632597
http://dx.doi.org/10.1038/ncomms4458