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Comprehensive analysis of miRNA expression in T-cell subsets of rheumatoid arthritis patients reveals defined signatures of naive and memory Tregs

Disturbed expression of microRNAs (miRNAs) in regulatory T cells (Tregs) leads to development of autoimmunity in experimental mouse models. However, the miRNA expression signature characterizing Tregs of autoimmune diseases, such as rheumatoid arthritis (RA) has not been determined yet. In this stud...

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Detalles Bibliográficos
Autores principales: Smigielska-Czepiel, K, van den Berg, A, Jellema, P, van der Lei, R J, Bijzet, J, Kluiver, J, Boots, A M H, Brouwer, E, Kroesen, B-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959220/
https://www.ncbi.nlm.nih.gov/pubmed/24401767
http://dx.doi.org/10.1038/gene.2013.69