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Monosodium Urate and Tumor Necrosis Factor-α Increase Apoptosis in Human Chondrocyte Cultures

Monosodium urate and tumor necrosis factor-α, are two potent mediators of separate inflammatory response pathways in arthritic joints where inflammation may be accompanied by the loss of chondrocyte vitality via apoptosis. To address this possibility in vitro, chondrocyte cultures were employed to d...

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Detalles Bibliográficos
Autores principales: Malemud, Charles J, Sun, Yan, Pearlman, Eric, Ginley, Nell M, Awadallah, Amad, Wisler, Bradley A, Dennis, James E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959644/
https://www.ncbi.nlm.nih.gov/pubmed/24660115
http://dx.doi.org/10.4172/2161-1149.1000113