Hypercholesterolemia Induces Oxidant Stress That Accelerates the Ageing of Hematopoietic Stem Cells

BACKGROUND: Clinical studies suggest that hypercholesterolemia may cause ageing in hematopoietic stem cells (HSCs) because ageing‐associated alterations were found in peripheral blood cells and their bone marrow residing precursors in patients with advanced atherosclerosis. We hypothesized that hype...

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Detalles Bibliográficos
Autores principales: Tie, Guodong, Messina, Katharine E., Yan, Jinglian, Messina, Julia A., Messina, Louis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959695/
https://www.ncbi.nlm.nih.gov/pubmed/24470519
http://dx.doi.org/10.1161/JAHA.113.000241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959695/
https://www.ncbi.nlm.nih.gov/pubmed/24470519
http://dx.doi.org/10.1161/JAHA.113.000241

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