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Deletion of Krüppel‐Like Factor 4 in Endothelial and Hematopoietic Cells Enhances Neointimal Formation Following Vascular Injury

BACKGROUND: Krüppel‐like factor 4 (Klf4) is involved in a variety of cellular functions by activating or repressing the transcription of multiple genes. Results of previous studies showed that tamoxifen‐inducible global deletion of the Klf4 gene in mice accelerated neointimal formation following vas...

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Detalles Bibliográficos
Autores principales: Yoshida, Tadashi, Yamashita, Maho, Horimai, Chihiro, Hayashi, Matsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959705/
https://www.ncbi.nlm.nih.gov/pubmed/24470523
http://dx.doi.org/10.1161/JAHA.113.000622