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The Cdk5 inhibitor Roscovitine increases LTP induction in corticostriatal synapses

In corticostriatal synapses, LTD (long-term depression) and LTP (long-term potentiation) are modulated by the activation of DA (dopamine) receptors, with LTD being the most common type of long-term plasticity induced using the standard stimulation protocols. In particular, activation of the D1 signa...

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Detalles Bibliográficos
Autores principales: Miranda-Barrientos, Jorge, Nieto-Mendoza, Elizabeth, Hernández-Echeagaray, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959759/
https://www.ncbi.nlm.nih.gov/pubmed/24555476
http://dx.doi.org/10.1042/AN20140006