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The Cdk5 inhibitor Roscovitine increases LTP induction in corticostriatal synapses
In corticostriatal synapses, LTD (long-term depression) and LTP (long-term potentiation) are modulated by the activation of DA (dopamine) receptors, with LTD being the most common type of long-term plasticity induced using the standard stimulation protocols. In particular, activation of the D1 signa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Neurochemistry
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959759/ https://www.ncbi.nlm.nih.gov/pubmed/24555476 http://dx.doi.org/10.1042/AN20140006 |