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RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization

Prostate cancer (PCa) metastasis to bone is lethal and there is no adequate animal model for studying the mechanisms underlying the metastatic process. Here, we report that receptor activator of NF-κB ligand (RANKL) expressed by PCa cells consistently induced colonization or metastasis to bone in an...

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Detalles Bibliográficos
Autores principales: Chu, Gina Chia-Yi, Zhau, Haiyen E, Wang, Ruoxiang, Rogatko, André, Feng, Xu, Zayzafoon, Majd, Liu, Youhua, Farach-Carson, Mary C, You, Sungyong, Kim, Jayoung, Freeman, Michael R, Chung, Leland W K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959765/
https://www.ncbi.nlm.nih.gov/pubmed/24478054
http://dx.doi.org/10.1530/ERC-13-0548