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pHTomato: A genetically-encoded indicator that enables multiplex interrogation of synaptic activity

The usefulness of genetically-encoded probes for optical monitoring of neuronal activity and brain circuits would be greatly advanced by the generation of multiple indicators with non-overlapping color spectra. Most existing indicators are derived from or spectrally convergent on GFP. We generated a...

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Detalles Bibliográficos
Autores principales: Li, Yulong, Tsien, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959862/
https://www.ncbi.nlm.nih.gov/pubmed/22634730
http://dx.doi.org/10.1038/nn.3126