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Diurnal Patterns of Soluble Amyloid Precursor Protein Metabolites in the Human Central Nervous System
The amyloid-β (Aβ) protein is diurnally regulated in both the cerebrospinal fluid and blood in healthy adults; circadian amplitudes decrease with aging and the presence of cerebral Aβ deposits. The cause of the Aβ diurnal pattern is poorly understood. One hypothesis is that the Amyloid Precursor Pro...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960093/ https://www.ncbi.nlm.nih.gov/pubmed/24646516 http://dx.doi.org/10.1371/journal.pone.0089998 |