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Functional Mechanism of C-Terminal Tail in the Enzymatic Role of Porcine Testicular Carbonyl Reductase: A Combined Experiment and Molecular Dynamics Simulation Study of the C-Terminal Tail in the Enzymatic Role of PTCR

Porcine testicular carbonyl reductase, PTCR which is one of the short chain dehydrogenases/reductases (SDR) superfamily catalyzes the NADPH-dependent reduction of carbonyl compounds including steroids and prostaglandins. Previously we reported C- terminal tail of PTCR was deleted due to a nonsynonym...

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Detalles Bibliográficos
Autores principales: Son, Minky, Bang, Woo Young, Park, Chanin, Lee, Yuno, Kwon, Seul Gi, Kim, Sam Woong, Kim, Chul Wook, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960098/
https://www.ncbi.nlm.nih.gov/pubmed/24646606
http://dx.doi.org/10.1371/journal.pone.0090712