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Roles of Autophagy in MPP(+)-Induced Neurotoxicity In Vivo: The Involvement of Mitochondria and α-Synuclein Aggregation

Macroautophagy (also known as autophagy) is an intracellular self-eating mechanism and has been proposed as both neuroprotective and neurodestructive in the central nervous system (CNS) neurodegenerative diseases. In the present study, the role of autophagy involving mitochondria and α-synuclein was...

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Detalles Bibliográficos
Autores principales: Hung, Kai-Chih, Huang, Hui-Ju, Lin, Ming-Wei, Lei, Yen-Ping, Lin, Anya Maan-yuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960112/
https://www.ncbi.nlm.nih.gov/pubmed/24646838
http://dx.doi.org/10.1371/journal.pone.0091074