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The Notch Pathway Is Important in Maintaining the Cancer Stem Cell Population in Pancreatic Cancer

BACKGROUND: Pancreatic cancer stem cells (CSCs) represent a small subpopulation of pancreatic cancer cells that have the capacity to initiate and propagate tumor formation. However, the mechanisms by which pancreatic CSCs are maintained are not well understood or characterized. METHODS: Expression o...

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Detalles Bibliográficos
Autores principales: Abel, Ethan V., Kim, Edward J., Wu, Jingjiang, Hynes, Mark, Bednar, Filip, Proctor, Erica, Wang, Lidong, Dziubinski, Michele L., Simeone, Diane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960140/
https://www.ncbi.nlm.nih.gov/pubmed/24647545
http://dx.doi.org/10.1371/journal.pone.0091983