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MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia

MYCN is an oncogene frequently overexpressed in pediatric solid tumors whereas few evidences suggest his involvement in the pathogenesis of haematologic malignancies. Here we show that MYCN is overexpressed in a relevant proportion (40 to 50%) of adult and pediatric T-cell acute lymphoblastic leukem...

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Detalles Bibliográficos
Autores principales: Astolfi, Annalisa, Vendemini, Francesca, Urbini, Milena, Melchionda, Fraia, Masetti, Riccardo, Franzoni, Monica, Libri, Virginia, Serravalle, Salvatore, Togni, Marco, Paone, Giuseppina, Montemurro, Luca, Bressanin, Daniela, Chiarini, Francesca, Martelli, Alberto M., Tonelli, Roberto, Pession, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960194/
https://www.ncbi.nlm.nih.gov/pubmed/24334727