Cargando…
MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia
MYCN is an oncogene frequently overexpressed in pediatric solid tumors whereas few evidences suggest his involvement in the pathogenesis of haematologic malignancies. Here we show that MYCN is overexpressed in a relevant proportion (40 to 50%) of adult and pediatric T-cell acute lymphoblastic leukem...
Autores principales: | Astolfi, Annalisa, Vendemini, Francesca, Urbini, Milena, Melchionda, Fraia, Masetti, Riccardo, Franzoni, Monica, Libri, Virginia, Serravalle, Salvatore, Togni, Marco, Paone, Giuseppina, Montemurro, Luca, Bressanin, Daniela, Chiarini, Francesca, Martelli, Alberto M., Tonelli, Roberto, Pession, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960194/ https://www.ncbi.nlm.nih.gov/pubmed/24334727 |
Ejemplares similares
-
Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels
por: Bressanin, Daniela, et al.
Publicado: (2012) -
Synergistic Cytotoxic Effect of L-Asparaginase Combined with Decitabine as a Demethylating Agent in Pediatric T-ALL, with Specific Epigenetic Signature
por: Serravalle, Salvatore, et al.
Publicado: (2016) -
Impact of Inflammatory Cytokine Gene Polymorphisms on Developing Acute Graft-versus-Host Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
por: Masetti, Riccardo, et al.
Publicado: (2015) -
Identification of a cytogenetic and molecular subgroup of acute myeloid leukemias showing sensitivity to L-Asparaginase
por: Bertuccio, Salvatore Nicola, et al.
Publicado: (2017) -
Molecular Signature of Biological Aggressiveness in Clear Cell Sarcoma of the Kidney (CCSK)
por: Fiore, Michele, et al.
Publicado: (2023)