A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation

TSC2 (Tuberous sclerosis complex 2) is an important tumour suppressor gene, mutations within which are linked to the development of tuberous sclerosis and implicated in multiple tumour types. TSC2 protein complexes with TSC1 and blocks the ability of the Rheb (Ras homolog enriched in brain) GTPase t...

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Detalles Bibliográficos
Autores principales: Munkley, Jennifer, Rajan, Prabhakar, Laferty, Nicholas P., Dalgliesh, Caroline, Jackson, Robert M., Robson, Craig N., Leung, Hing Y., Elliott, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960195/
https://www.ncbi.nlm.nih.gov/pubmed/24318044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960195/
https://www.ncbi.nlm.nih.gov/pubmed/24318044

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