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Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death

The Ras family of small GTPases transmits extracellular signals that regulate cell growth, differentiation, motility and death. Ras signaling is constitutively active in a large number of human cancers. Ras can also regulate autophagy by affecting several signaling pathways including the mTOR pathwa...

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Detalles Bibliográficos
Autores principales: Schmukler, Eran, Wolfson, Eya, Haklai, Roni, Elad-Sfadia, Galit, Kloog, Yoel, Pinkas-Kramarski, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960199/
https://www.ncbi.nlm.nih.gov/pubmed/24368422