AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine

Activation-induced cytidine deaminase (AID) was originally identified as an inducer of somatic hypermutation (SHM) and class switch recombination (CSR) in immunoglobulin genes. However, AID can also cause mutations in host genes and contribute to cancer progression and drug resistance. In this study...

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Detalles Bibliográficos
Autores principales: Tsai, Chiou-Tsun, Yang, Pei-Ming, Chern, Ting-Rong, Chuang, Shu-Hui, Lin, Jung-Hsin, Klemm, Lars, Müschen, Markus, Chen, Ching-Chow
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960202/
https://www.ncbi.nlm.nih.gov/pubmed/24457556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960202/
https://www.ncbi.nlm.nih.gov/pubmed/24457556

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