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Bactericidal Antibiotics Increase Hydroxyphenyl Fluorescein Signal by Altering Cell Morphology

It was recently proposed that for bactericidal antibiotics a common killing mechanism contributes to lethality involving indirect stimulation of hydroxyl radical (OH(•)) formation. Flow cytometric detection of OH(•) by hydroxyphenyl fluorescein (HPF) probe oxidation was used to support this hypothes...

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Detalles Bibliográficos
Autores principales: Paulander, Wilhelm, Wang, Ying, Folkesson, Anders, Charbon, Godefroid, Løbner-Olesen, Anders, Ingmer, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960231/
https://www.ncbi.nlm.nih.gov/pubmed/24647480
http://dx.doi.org/10.1371/journal.pone.0092231