The Anti-Hypercholesterolemic Effect of Low p53 Expression Protects Vascular Endothelial Function in Mice

AIMS: To demonstrate that p53 modulates endothelial function and the stress response to a high-fat western diet (WD). METHODS AND RESULTS: Three-month old p53(+/+) wild type (WT) and p53(+/−) male mice were fed a regular or WD for 3 months. Plasma levels of total cholesterol (TC) and LDL-cholesterol...

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Detalles Bibliográficos
Autores principales: Leblond, Francois, Poirier, Steve, Yu, Carol, Duquette, Natacha, Mayer, Gaetan, Thorin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960235/
https://www.ncbi.nlm.nih.gov/pubmed/24647794
http://dx.doi.org/10.1371/journal.pone.0092394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960235/
https://www.ncbi.nlm.nih.gov/pubmed/24647794
http://dx.doi.org/10.1371/journal.pone.0092394

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