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The Collaborative Cross as a Resource for Modeling Human Disease: CC011/Unc, a New Mouse Model for Spontaneous Colitis

Inflammatory bowel disease (IBD) is an immune-mediated condition driven by improper responses to intestinal microflora in the context of environmental and genetic background. GWAS in humans have identified many loci associated with IBD, but animal models are valuable for dissecting the underlying mo...

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Detalles Bibliográficos
Autores principales: Rogala, Allison R., Morgan, Andrew P., Christensen, Alexis M., Gooch, Terry J., Bell, Timothy A., Miller, Darla R., Godfrey, Virginia L., de Villena, Fernando Pardo-Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960486/
https://www.ncbi.nlm.nih.gov/pubmed/24487921
http://dx.doi.org/10.1007/s00335-013-9499-2