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Enhanced self-administration of the CB(1) receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms

Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with intravenous drug self-administration procedure to...

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Detalles Bibliográficos
Autores principales: Amchova, Petra, Kucerova, Jana, Giugliano, Valentina, Babinska, Zuzana, Zanda, Mary T., Scherma, Maria, Dusek, Ladislav, Fadda, Paola, Micale, Vincenzo, Sulcova, Alexandra, Fratta, Walter, Fattore, Liana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960502/
https://www.ncbi.nlm.nih.gov/pubmed/24688470
http://dx.doi.org/10.3389/fphar.2014.00044