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Oct2 and Obf1 as Facilitators of B:T Cell Collaboration during a Humoral Immune Response

The Oct2 protein, encoded by the Pou2f2 gene, was originally predicted to act as a DNA binding transcriptional activator of immunoglobulin (Ig) in B lineage cells. This prediction flowed from the earlier observation that an 8-bp sequence, the “octamer motif,” was a highly conserved component of most...

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Detalles Bibliográficos
Autores principales: Corcoran, Lynn, Emslie, Dianne, Kratina, Tobias, Shi, Wei, Hirsch, Susanne, Taubenheim, Nadine, Chevrier, Stephane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960507/
https://www.ncbi.nlm.nih.gov/pubmed/24688485
http://dx.doi.org/10.3389/fimmu.2014.00108