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Oct2 and Obf1 as Facilitators of B:T Cell Collaboration during a Humoral Immune Response
The Oct2 protein, encoded by the Pou2f2 gene, was originally predicted to act as a DNA binding transcriptional activator of immunoglobulin (Ig) in B lineage cells. This prediction flowed from the earlier observation that an 8-bp sequence, the “octamer motif,” was a highly conserved component of most...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960507/ https://www.ncbi.nlm.nih.gov/pubmed/24688485 http://dx.doi.org/10.3389/fimmu.2014.00108 |