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Tea polyphenols induced apoptosis of breast cancer cells by suppressing the expression of Survivin

To study the mechanism of tea polyphenols (TP)-induced apoptosis of breast cancer cells. Proliferation of MCF-7 and SK-BR-3 cells was evaluated by MTT assays. Cellular ultrastructure was examined by electron microscopy. Apoptosis was detected by TUNEL. PCNA、 Cyclin D1、 Cyclin E and Survivin expressi...

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Detalles Bibliográficos
Autores principales: Chen, Xuesong, Li, Yu, Lin, Qiushi, Wang, Yan, Sun, Hong, Wang, Jian, Cui, Guoquan, Cai, Li, Dong, Xiaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960584/
https://www.ncbi.nlm.nih.gov/pubmed/24646833
http://dx.doi.org/10.1038/srep04416