Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells

BACKGROUND: Recently several microRNAs (miRNAs) have been found to be regulated by genistein in cancer cells. In this study, we focused on the gene regulatory effect of genistein on microRNA and its target genes in prostate cancer (PC). METHODS: Initially, we investigated the effect of genistein on...

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Detalles Bibliográficos
Autores principales: Hirata, H, Hinoda, Y, Shahryari, V, Deng, G, Tanaka, Y, Tabatabai, Z L, Dahiya, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960620/
https://www.ncbi.nlm.nih.gov/pubmed/24504368
http://dx.doi.org/10.1038/bjc.2014.48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960620/
https://www.ncbi.nlm.nih.gov/pubmed/24504368
http://dx.doi.org/10.1038/bjc.2014.48

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