Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets

BACKGROUND: Monoclonal antibody (mAb) therapy for the treatment of solid and haematologic malignancies has shown poor response rates as a monotherapy. Furthermore, its use is limited to tumours expressing certain molecular targets. It has been shown that single-dose radiation can induce immunogenic...

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Detalles Bibliográficos
Autores principales: Wattenberg, M M, Kwilas, A R, Gameiro, S R, Dicker, A P, Hodge, J W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960628/
https://www.ncbi.nlm.nih.gov/pubmed/24556625
http://dx.doi.org/10.1038/bjc.2014.79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960628/
https://www.ncbi.nlm.nih.gov/pubmed/24556625
http://dx.doi.org/10.1038/bjc.2014.79

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