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Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors

In the adult thymus, the development of self-tolerant thymocytes requires interactions with thymic epithelial cells (TECs). Although both cortical and medullary TECs (cTECs/mTECs) are known to arise from common bipotent TEC progenitors, the phenotype of these progenitors and the timing of the emerge...

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Detalles Bibliográficos
Autores principales: Baik, Song, Jenkinson, Eric J, Lane, Peter J L, Anderson, Graham, Jenkinson, William E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960635/
https://www.ncbi.nlm.nih.gov/pubmed/23299414
http://dx.doi.org/10.1002/eji.201243209