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Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors
In the adult thymus, the development of self-tolerant thymocytes requires interactions with thymic epithelial cells (TECs). Although both cortical and medullary TECs (cTECs/mTECs) are known to arise from common bipotent TEC progenitors, the phenotype of these progenitors and the timing of the emerge...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BlackWell Publishing Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960635/ https://www.ncbi.nlm.nih.gov/pubmed/23299414 http://dx.doi.org/10.1002/eji.201243209 |