Quantification of Protoporphyrin IX Accumulation in Glioblastoma Cells: A New Technique

Introduction. 5-Aminolevulinic Acid (5-ALA) is a precursor of heme synthesis. A metabolite, protoporphyrin IX (PpIX), selectively accumulates in neoplastic tissue including glioblastoma. Presurgical administration of 5-ALA forms the basis of fluorescence-guided resection (FGR) of glioblastoma (GBM)...

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Detalles Bibliográficos
Autores principales: Lawrence, Johnathan E., Patel, Ashish S., Rovin, Richard A., Belton, Robert J., Bammert, Catherine E., Steele, Christopher J., Winn, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960765/
https://www.ncbi.nlm.nih.gov/pubmed/24729904
http://dx.doi.org/10.1155/2014/405360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960765/
https://www.ncbi.nlm.nih.gov/pubmed/24729904
http://dx.doi.org/10.1155/2014/405360

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