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Synthesis and antinociceptive activity of novel mannich base derivatives of some new fused 3,5-pyrazolidinedione
In the present study, a novel series of mannich bases 1-((1-substituted ethyl-1H-benzo[d] imidazol-2-yl) methyl)-2-substituted phenylpyrazolidine-3,5-dione 3(a-l) were synthesized and evaluated as antinociceptive agents in mice by Eddy's hot plate and acetic acid-induced writhing models. The st...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960794/ https://www.ncbi.nlm.nih.gov/pubmed/24696816 http://dx.doi.org/10.4103/2231-4040.126993 |