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Solution and crystal structures of a C-terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB)

The eukaryotic polypyrimidine tract binding protein (PTB) serves primarily as a regulator of alternative splicing of messenger RNA, but is also co-opted to other roles such as RNA localisation and translation initiation from internal ribosome entry sites. The neuronal paralogue of PTB (nPTB) is 75%...

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Detalles Bibliográficos
Autores principales: Joshi, Amar, Esteve, Vicent, Buckroyd, Adrian N., Blatter, Markus, Allain, Frédéric H.-T., Curry, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961105/
https://www.ncbi.nlm.nih.gov/pubmed/24688880
http://dx.doi.org/10.7717/peerj.305