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CD154 blockade modulates the ratio of Treg to Th1 cells and prolongs the survival of allogeneic corneal grafts in mice

Administration of anti-CD154 monoclonal antibody (mAb) may prolong the survival of an allograft; however, the associated therapeutic mechanisms remain poorly understood. This study aimed to evaluate the effects of anti-CD154 mAb on T-cell responses in a mouse model of corneal allograft transplantati...

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Detalles Bibliográficos
Autores principales: TAN, XIAOBO, ZENG, HUI, JIE, YING, ZHANG, YINGNAN, XU, QING, PAN, ZHIQIANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961129/
https://www.ncbi.nlm.nih.gov/pubmed/24660031
http://dx.doi.org/10.3892/etm.2014.1527