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Probabilistic Approach to Predicting Substrate Specificity of Methyltransferases
We present a general probabilistic framework for predicting the substrate specificity of enzymes. We designed this approach to be easily applicable to different organisms and enzymes. Therefore, our predictive models do not rely on species-specific properties and use mostly sequence-derived data. Ma...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961171/ https://www.ncbi.nlm.nih.gov/pubmed/24651469 http://dx.doi.org/10.1371/journal.pcbi.1003514 |