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Probabilistic Approach to Predicting Substrate Specificity of Methyltransferases

We present a general probabilistic framework for predicting the substrate specificity of enzymes. We designed this approach to be easily applicable to different organisms and enzymes. Therefore, our predictive models do not rely on species-specific properties and use mostly sequence-derived data. Ma...

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Detalles Bibliográficos
Autores principales:	Szczepińska, Teresa, Kutner, Jan, Kopczyński, Michał, Pawłowski, Krzysztof, Dziembowski, Andrzej, Kudlicki, Andrzej, Ginalski, Krzysztof, Rowicka, Maga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961171/ https://www.ncbi.nlm.nih.gov/pubmed/24651469 http://dx.doi.org/10.1371/journal.pcbi.1003514

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