Asymmetry in Family History Implicates Nonstandard Genetic Mechanisms: Application to the Genetics of Breast Cancer

Genome-wide association studies typically target inherited autosomal variants, but less studied genetic mechanisms can play a role in complex disease. Sex-linked variants aside, three genetic phenomena can induce differential risk in maternal versus paternal lineages of affected individuals: 1. mate...

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Detalles Bibliográficos
Autores principales: Weinberg, Clarice R., Shi, Min, DeRoo, Lisa A., Taylor, Jack A., Sandler, Dale P., Umbach, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961172/
https://www.ncbi.nlm.nih.gov/pubmed/24651610
http://dx.doi.org/10.1371/journal.pgen.1004174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961172/
https://www.ncbi.nlm.nih.gov/pubmed/24651610
http://dx.doi.org/10.1371/journal.pgen.1004174

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