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Sugar and Chromosome Stability: Clastogenic Effects of Sugars in Vitamin B6-Deficient Cells

Pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, has been implicated in preventing human pathologies, such as diabetes and cancer. However, the mechanisms underlying the beneficial effects of PLP are still unclear. Using Drosophila as a model system, we show that PLP deficiency, caused e...

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Detalles Bibliográficos
Autores principales: Marzio, Antonio, Merigliano, Chiara, Gatti, Maurizio, Vernì, Fiammetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961173/
https://www.ncbi.nlm.nih.gov/pubmed/24651653
http://dx.doi.org/10.1371/journal.pgen.1004199