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Sugar and Chromosome Stability: Clastogenic Effects of Sugars in Vitamin B6-Deficient Cells
Pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, has been implicated in preventing human pathologies, such as diabetes and cancer. However, the mechanisms underlying the beneficial effects of PLP are still unclear. Using Drosophila as a model system, we show that PLP deficiency, caused e...
Autores principales: | Marzio, Antonio, Merigliano, Chiara, Gatti, Maurizio, Vernì, Fiammetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961173/ https://www.ncbi.nlm.nih.gov/pubmed/24651653 http://dx.doi.org/10.1371/journal.pgen.1004199 |
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