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Antitumor and immunomodulatory effects of low-dose 5-FU on hepatoma 22 tumor-bearing mice

Low-dose 5-fluorouracil (5-FU), a widely used chemotherapeutic, has been reported to have immunomodulatory effects. This study aimed to evaluate the optimal dose of 5-FU that produces antitumor and immunomodulatory effects. In a hepatoma 22 tumor-bearing mouse model, 0, 10, 20 and 40 mg/kg 5-FU (i.p...

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Detalles Bibliográficos
Autores principales: CAO, ZHIYUN, ZHANG, ZHIDENG, HUANG, ZHENGRONG, WANG, RONGPING, YANG, AILIAN, LIAO, LIANMING, DU, JIAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961200/
https://www.ncbi.nlm.nih.gov/pubmed/24660037
http://dx.doi.org/10.3892/ol.2014.1856