DUF1220 Dosage Is Linearly Associated with Increasing Severity of the Three Primary Symptoms of Autism

One of the three most frequently documented copy number variations associated with autism spectrum disorder (ASD) is a 1q21.1 duplication that encompasses sequences encoding DUF1220 protein domains, the dosage of which we previously implicated in increased human brain size. Further, individuals with...

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Detalles Bibliográficos
Autores principales: Davis, Jonathan M., Searles, Veronica B., Anderson, Nathan, Keeney, Jonathon, Dumas, Laura, Sikela, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961203/
https://www.ncbi.nlm.nih.gov/pubmed/24651471
http://dx.doi.org/10.1371/journal.pgen.1004241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961203/
https://www.ncbi.nlm.nih.gov/pubmed/24651471
http://dx.doi.org/10.1371/journal.pgen.1004241

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