A Screen Identifies the Oncogenic Micro-RNA miR-378a-5p as a Negative Regulator of Oncogene-Induced Senescence

Oncogene-induced senescence (OIS) can occur in response to hyperactive oncogenic signals and is believed to be a fail-safe mechanism protecting against tumorigenesis. To identify new factors involved in OIS, we performed a screen for microRNAs that can overcome or inhibit OIS in human diploid fibrob...

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Detalles Bibliográficos
Autores principales: Kooistra, Susanne Marije, Nørgaard, Lise Christine Rudkjær, Lees, Michael James, Steinhauer, Cornelia, Johansen, Jens Vilstrup, Helin, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961217/
https://www.ncbi.nlm.nih.gov/pubmed/24651706
http://dx.doi.org/10.1371/journal.pone.0091034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961217/
https://www.ncbi.nlm.nih.gov/pubmed/24651706
http://dx.doi.org/10.1371/journal.pone.0091034

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