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Protease-Activated Receptor-2 Activation Contributes to House Dust Mite-Induced IgE Responses in Mice

Aeroallergens such as house dust mite (HDM), cockroach, and grass or tree pollen are innocuous substances that can induce allergic sensitization upon inhalation. The serine proteases present in these allergens are thought to activate the protease-activated receptor (PAR)-2, on the airway epithelium,...

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Detalles Bibliográficos
Autores principales: Post, Sijranke, Heijink, Irene H., Petersen, Arjen H., de Bruin, Harold G., van Oosterhout, Antoon J. M., Nawijn, Martijn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961228/
https://www.ncbi.nlm.nih.gov/pubmed/24651123
http://dx.doi.org/10.1371/journal.pone.0091206